Paracetamol has Side Effects in Digestive Tract, Kidney and Heart of Elderly People: Study

We often use paracetamol without consulting a doctor for mild fever or body pain. While it provides temporary relief, its use can be extremely harmful, especially for the elderly aged 65 and above. According to a recent study conducted in Britain, the use of paracetamol can lead to several digestive tract, kidney and heart-related problems in the long run.

Paracetamol and Bone Diseases

Paracetamol is recommended as the first-line treatment for bone diseases like osteoarthritis—a chronic condition causing pain, stiffness and swelling in the joints, as it is considered effective and relatively safe. However, recent research raises concerns about its long-term effects. Studies suggest that prolonged use can lead to severe side effects, including ulcers and bleeding in the digestive tract.

Study Findings

Researchers at the University of Nottingham, UK, analyzed health records of 1.8 lakh people aged 65 and above who were prescribed paracetamol two or more times within six months. Their outcomes were compared to 4.02 lakh individuals of the same age who did not use the drug frequently. The study is based on clinical practice research data conducted between 1998 and 2018. It revealed:

  • 24% increased risk of peptic ulcers (bleeding)
  • 19% higher chance of chronic kidney disease
  • 9% greater risk of heart failure
  • 7% increase in hypertension

“Due to its perceived safety, paracetamol has long been recommended as the first line drug treatment for osteoarthritis by many treatment guidelines, especially in older people who are at higher risk of drug-related complications,” said Dr. Weiya Zhang, lead researcher from the University of Nottingham’s School of Medicine.

Dr. Zhang emphasized that the use of this medication as a first-line painkiller for chronic conditions like osteoarthritis in the elderly should be reconsidered.

This study underscores the importance of consulting a doctor before taking paracetamol, particularly for long-term use in older adults. Awareness of its potential risks can help ensure safer treatment alternatives for managing chronic pain and conditions.

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